What symptom may accompany prostate gland abnormalities noted during a DRE?

The symptom associated with prostate gland abnormalities found during a digital rectal examination (DRE) can be elevated serum acid phosphatase levels. This enzyme is often released by prostate cells, including those associated with malignancies or abnormalities in the prostate, indicating potential prostate pathology.

Elevated serum acid phosphatase is particularly noteworthy in the context of prostate cancer, where it serves as a tumor marker. This elevation suggests that the prostate may be undergoing pathological changes—whether benign or malignant. Understanding this relationship can aid in early detection and proper management of conditions affecting the prostate.

Other symptoms, while relevant to prostate issues, do not specifically correlate with serum acid phosphatase levels. Pain during urination and frequent urination at night often relate to benign conditions like benign prostatic hyperplasia (BPH) or prostatitis, rather than directly indicating abnormal levels of acid phosphatase. Unexplained weight loss could signal advanced disease but is not specifically tied to prostate gland abnormalities in the context of a DRE.